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Article

Haplotype-based association study of TCF7L2 gene variants with the development of diabetic retinopathy in an Iranian population.

Ophthalmic genetics - 1 Jun 2024

Alidoust Leila, Sharafshah Alireza, Keshavarz Parvaneh

Abstract excerpt

BACKGROUND: Diabetic retinopathy (DR) is recognized as one of the most prevalent complications of diabetes and a major cause of morbidity. Transcription factor 7-like 2 (TCF7L2), a pivotal component in the Wnt-signaling pathway, plays a significant role in β-cell development, blood-glucose homeostasis, cell survival, cell migration, and cell proliferation. Thus, this study aimed to assess the association between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38514248
DOI: 10.1080/13816810.2024.2318611

Genes

TCF7L2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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