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Article

Sigma Factors: Key Molecules in <i>Mycobacterium tuberculosis</i> Physiology and Virulence

17 Jan 2014

Abstract excerpt

Rapid adaptation to changing environments is one of the keys to the success of microorganisms. Since infection is a dynamic process, it is possible to predict that Mycobacterium tuberculosis adaptation involves continuous modulation of its global transcriptional profile in response to the changing environment found in the human body. In the last 18 years several studies have stressed the role of sigma (σ) factors...

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PMID: 26082107
DOI: 10.1128/microbiolspec.mgm2-0007-2013

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