Article

Dopamine Agonists for the Treatment of Pituitary Tumors: From Ergot Extracts to Next Generation Therapies

2022-11-03

Abstract excerpt

Abstract Dopamine agonists are a key tool in the therapeutic arsenal of endocrinologists worldwide. They exert their effects by binding to dopamine 2 (D2) receptors expressed by pituitary tumor cells, to modulate hormonal secretion and tumor size. They are the established first-line treatment for prolactinomas which express high levels of D2 receptors. Growing data supports their use as an adjuvant treatment optio...

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Literature Corpus work: 72039ff9-06a4-529c-a20e-c90a638cbed2
DOI: 10.22541/au.166746244.47678512/v1

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