Article
Allergic sensitization is associated with inadequate antioxidant responses in mice and men.
Allergy - 1 Oct 2015
Utsch L, Folisi C, Akkerdaas J H, Logiantara A, van de Pol M A, van der Zee J S, Krop E J M, Lutter R, van Ree R, van Rijt L S
Abstract excerpt
BACKGROUND: Allergies arise from aberrant Th2 responses to allergens. The processes involved in the genesis of allergic sensitization remain elusive. Some allergens such as derived from house dust mites have proteolytic activity which can induce oxidative stress in vivo. A reduced capacity of the host to control oxidative stress might prime for allergic sensitization. METHODS: Two different strains of mice were...
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