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EC-SOD and the response to inflammatory reactions and aging in mouse lung.

Free radical biology & medicine - 15 May 2002

Sentman Marie Louise, Brännström Thomas, Marklund Stefan L

Abstract excerpt

The lung is exposed to high oxygen tension and oxygen free radicals have been implicated in many pathologies of the organ. Extracellular superoxide dismutase occurs in high concentration in the lung and protects against hyperoxia-induced inflammation. We hypothesized that the enzyme might ameliorate other types of inflammation as well as aging-related changes of the organ. Tracheal instillation of endotoxin plus...

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PMID: 12008113
DOI: 10.1016/s0891-5849(02)00790-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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