Article
Both the variability and level of mouse allergen exposure influence the phenotype of the immune response in workers at a mouse facility.
The Journal of allergy and clinical immunology - 1 Aug 2011
Peng Roger D, Paigen Beverly, Eggleston Peyton A, Hagberg Karol A, Krevans Mary, Curtin-Brosnan Jean, Benson Cristy, Shreffler Wayne G, Matsui Elizabeth C
Abstract excerpt
BACKGROUND: The role of natural aeroallergen exposure in modulating allergen-specific immune responses is not well understood. OBJECTIVE: We sought to examine relationships between mouse allergen exposure and mouse-specific immune responses. METHODS: New employees (n = 179) at a mouse facility underwent repeated assessment of mouse allergen exposure, skin prick tests (SPTs), and measurement of mouse-specific IgG...
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