Article
Pharmacogenetics of human cytosolic sulfotransferases.
Oncogene - 13 Mar 2006
Nowell S, Falany C N
Abstract excerpt
Cytosolic sulfotransferases (SULTs) are phase II detoxification enzymes that are involved in the biotransformation of a wide variety of structurally diverse endo- and xenobiotics, including many therapeutic agents and endogenous steroids. Single-nucleotide polymorphisms (SNPs) in SULTs have functional consequences on the translated protein. For the most part, these SNPs are fairly uncommon in the population, but...
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