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Article

A novel association between COMT and BDNF gene polymorphisms and likelihood of symptomatic dysphagia in older people.

Neurogastroenterology and motility - 1 Sept 2015

Nimmons D, Pendleton N, Payton A, Ollier W, Horan M, Wilkinson J, Hamdy S

Abstract excerpt

BACKGROUND: Catechol-O-methyl transferase (COMT) and brain-derived neurotrophic factor (BDNF) are neuro-modulatory proteins that have been demonstrated to affect cortical plasticity, which in turn has been shown to affect age-related changes and neuronal functioning in humans. Here, we tested the hypothesis that single nucleotide polymorphisms (SNP) within COMT and BDNF genes are associated with dysphagia in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26073434
DOI: 10.1111/nmo.12609

Genes

BDNF
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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