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Article

Analysis of functional polymorphisms in three synaptic plasticity-related genes (BDNF, COMT AND UCHL1) in Alzheimer's disease in Colombia.

Neuroscience research - 1 Jul 2006

Forero Diego A, Benítez Bruno, Arboleda Gonzalo, Yunis Juan J, Pardo Rodrigo, Arboleda Humberto

Abstract excerpt

In recent years, it has been proposed that synaptic dysfunction may be an important etiological factor for Alzheimer's disease (AD). This hypothesis has important implications for the analysis of AD genetic risk in case-control studies. In the present work, we analyzed common functional polymorphisms in three synaptic plasticity-related genes (brain-derived neurotrophic factor, BDNF Val66Met; catechol-O-methyl...

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Source

Identifiers

PMID: 16698101
DOI: 10.1016/j.neures.2006.04.006

Genes

BDNF
COMT
UCHL1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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