Article
Polymorphisms in the catechol-o-methyltransferase gene and delirium in the elderly.
Dementia and geriatric cognitive disorders - 1 Jan 2011
van Munster Barbara C, Baas Frank, Tanck Michael W, de Rooij Sophia E J A
Abstract excerpt
BACKGROUND/AIMS: Catechol-O-methyltransferase, encoded by the COMT gene, is one of the enzymes that degrade dopamine. The aim of this study was to investigate whether polymorphisms in the COMT gene were associated with delirium. METHODS: Patients aged 65 years and older, acutely admitted to the medical department or to the surgical department following hip fracture, were included. rs4680, rs4818, and rs6269 were...
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