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Article

COMT gene val158met polymorphism in patients with dyspeptic symptoms.

Hepato-gastroenterology - 1 Jan 2000

Tahara Tomomitsu, Arisawa Tomiyasu, Shibata Tomoyuki, Nakamura Masakatsu, Wang Fangyu, Hirata Ichiro

Abstract excerpt

BACKGROUND/AIMS: The role of genetics in the susceptibility to functional dyspepsia (FD) is unclear. Catechol-O-methyltransferase (COMT) has been an important enzyme in brain gut axis and pain sensitivity. Polymorphism in codon 158 of the COMT gene influences its activity. This study aimed to clarify the association between COMT polymorphism and dyspepsia in a Japanese population. METHODOLOGY: 91 dyspeptics and...

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Source

Identifiers

PMID: 18705311

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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