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Article

Epistasis and balanced polymorphism influencing complex trait variation.

Nature - 5 May 2005

Kroymann Juergen, Mitchell-Olds Thomas

Abstract excerpt

Complex traits such as human disease, growth rate, or crop yield are polygenic, or determined by the contributions from numerous genes in a quantitative manner. Although progress has been made in identifying major quantitative trait loci (QTL), experimental constraints have limited our knowledge of small-effect QTL, which may be responsible for a large proportion of trait variation. Here, we identified and...

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PMID: 15875023
DOI: 10.1038/nature03480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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