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Article

Global Genetic Heterogeneity in Adaptive Traits.

Molecular biology and evolution - 27 Oct 2021

Lopez-Arboleda William Andres, Reinert Stephan, Nordborg Magnus, Korte Arthur

Abstract excerpt

Understanding the genetic architecture of complex traits is a major objective in biology. The standard approach for doing so is genome-wide association studies (GWAS), which aim to identify genetic polymorphisms responsible for variation in traits of interest. In human genetics, consistency across studies is commonly used as an indicator of reliability. However, if traits are involved in adaptation to the local...

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PMID: 34240182
DOI: 10.1093/molbev/msab208
PMCID: PMC8557469

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