Article
Social supports and serotonin transporter gene moderate depression in maltreated children.
Proceedings of the National Academy of Sciences of the United States of America - 7 Dec 2004
Kaufman Joan, Yang Bao-Zhu, Douglas-Palumberi Heather, Houshyar Shadi, Lipschitz Deborah, Krystal John H, Gelernter Joel
Abstract excerpt
In this study, measures of the quality and availability of social supports were found to moderate risk for depression associated with a history of maltreatment and the presence of the short (s) allele of the serotonin transporter gene promoter polymorphism (5-HTTLPR). The present investigation (i) replicates research in adults showing that 5-HTTLPR variation moderates the development of depression after stress,...
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