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Article

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data.

Bioinformatics (Oxford, England) - 15 Oct 2015

Gupta Namita T, Vander Heiden Jason A, Uduman Mohamed, Gadala-Maria Daniel, Yaari Gur, Kleinstein Steven H

Abstract excerpt

UNLABELLED: Advances in high-throughput sequencing technologies now allow for large-scale characterization of B cell immunoglobulin (Ig) repertoires. The high germline and somatic diversity of the Ig repertoire presents challenges for biologically meaningful analysis, which requires specialized computational methods. We have developed a suite of utilities, Change-O, which provides tools for advanced analyses of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26069265
DOI: 10.1093/bioinformatics/btv359
PMCID: PMC4793929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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