Article
Non-invasive fetal ABO genotyping in maternal plasma using real-time PCR.
Clinical chemistry and laboratory medicine - 1 Nov 2015
Song Wenqian, Zhou Shihang, Shao Linnan, Wang Ni, Pan Lingzi, Yu Weijian
Abstract excerpt
BACKGROUND: Fetal-maternal ABO incompatibility is a frequent cause of hemolytic disease of the fetus and newborn (HDFN). The routine serological testing of maternal IgG antibody level to predict HDFN shows low reliability. Non-invasive fetal ABO genotyping could provide a new avenue for predicting ABO-HDFN in early pregnancy. The aim of our study is to investigate the feasibility of fetal ABO genotyping in...
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