Article
[Application of RASSF1A to Noninvasive Fetal ABO Genotyping in Pregrnant Peripheral Plasma].
Zhongguo shi yan xue ye xue za zhi - 1 Aug 2016
Ma Ling, Liu Yan-Chun, Zhang Ruo-Yang, Zhou Xiao-Yu, Xun Jing-Ming
Abstract excerpt
OBJECTIVE: To investigate the feasibility of noninvasive fetal ABO genotyping based on RASSF1A gene with circulating cell-free fetal DNA(cffDNA) from maternal plasma. METHODS: DNA was extracted from the O group pregnant plasma, and the presence of cffDNA was confirmed by fetal DNA maker SRY and RASSF1A. B and non-O were detected by real-time PCR, and the genotyping results were evaluated by using the serologic...
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