Article
Use of maternal plasma for non-invasive prenatal diagnosis of fetal ABO genotypes.
Clinical chemistry and laboratory medicine - 1 Jan 2007
Meng Jin-Lai, Wang Xie-Tong, Wang Yu, Yue Ya-Fei, Wang Xin, Chen Zi-Jiang
Abstract excerpt
BACKGROUND: Measurement of free fetal DNA in maternal plasma opened a door for non-invasive prenatal diagnosis. Prenatal diagnosis of fetal ABO genotypes can provide a basis for the prevention and therapy of maternal-fetal incompatibility. We identified fetal ABO genotypes using fetal DNA in plasma from pregnant women with blood group O. The aim of the study was to investigate the accuracy and feasibility of this...
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