Article
Fecal microbiota composition differs between children with β-cell autoimmunity and those without.
Diabetes - 1 Apr 2013
de Goffau Marcus C, Luopajärvi Kristiina, Knip Mikael, Ilonen Jorma, Ruohtula Terhi, Härkönen Taina, Orivuori Laura, Hakala Saara, Welling Gjalt W, Harmsen Hermie J, Vaarala Outi
Abstract excerpt
The role of the intestinal microbiota as a regulator of autoimmune diabetes in animal models is well-established, but data on human type 1 diabetes are tentative and based on studies including only a few study subjects. To exclude secondary effects of diabetes and HLA risk genotype on gut microbiota, we compared the intestinal microbiota composition in children with at least two diabetes-associated autoantibodies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.