Article
[Testosterone suppresses oxidized low-density lipoprotein-induced vascular smooth muscle cell phenotypic transition and proliferation].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 Jun 2015
Zhou Wei, Liu Wei, Liao Hua, Cao Zhe, Xie Han, Zhang Shaoying, Chen Manhua
Abstract excerpt
OBJECTIVE: To investigate the inhibitory effect of testosterone on oxidized low-density lipoproteins (ox-LDL)-stimulated phenotypic transition and proliferation of vascular smooth muscle cells (VSMCs) in vitro, and explore its possible mechanisms. METHODS: Rat VSMCs were cultured using serum starvation method to make cell synchronization. Cells in vitro were divided into control group, ox-LDL group (treated with...
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