Article
DNA methylation at IL32 in juvenile idiopathic arthritis.
Scientific reports - 9 Jun 2015
Meyer Braydon, Chavez Raul A, Munro Jane E, Chiaroni-Clarke Rachel C, Akikusa Jonathan D, Allen Roger C, Craig Jeffrey M, Ponsonby Anne-Louise, Saffery Richard, Ellis Justine A
Abstract excerpt
Juvenile idiopathic arthritis (JIA) is the most common autoimmune rheumatic disease of childhood. We recently showed that DNA methylation at the gene encoding the pro-inflammatory cytokine interleukin-32 (IL32) is reduced in JIA CD4+ T cells. To extend this finding, we measured IL32 methylation i...
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