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Article

C/EBPα-p30 protein induces expression of the oncogenic long non-coding RNA UCA1 in acute myeloid leukemia.

Oncotarget - 30 Jul 2015

Hughes James M, Legnini Ivano, Salvatori Beatrice, Masciarelli Silvia, Marchioni Marcella, Fazi Francesco, Morlando Mariangela, Bozzoni Irene, Fatica Alessandro

Abstract excerpt

Accumulating evidences indicate that different long non-coding RNAs (lncRNAs) might play a relevant role in tumorigenesis, with their expression and function already associated to cancer development and progression. CCAAT/enhancer-binding protein-α (CEBPA) is a critical regulator of myeloid differentiation whose inactivation contributes to the development of acute myeloid leukemia (AML). Mutations in C/EBPα occur...

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Identifiers

PMID: 26053097
DOI: 10.18632/oncotarget.4069
PMCID: PMC4621908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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