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Article

Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice.

Diabetologia - 1 Sept 2015

Heppner Kristy M, Marks Sarah, Holland Jenna, Ottaway Nickki, Smiley David, Dimarchi Richard, Perez-Tilve Diego

Abstract excerpt

AIMS/HYPOTHESIS: We assessed the contribution of glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) signalling to thermogenesis induced by high-fat diet (HFD) consumption. Furthermore, we determined whether brown adipose tissue (BAT) activity contributes to weight loss induced by chronic subcutaneous treatment with the GLP-1R agonist, liraglutide, in a model of diet-induced obesity. METHODS: Metabolic phenotyping...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet, High-Fat

Share to Glucagon-Like Peptide 1

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Source

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Identifiers

PMID: 26049402
DOI: 10.1007/s00125-015-3651-3
PMCID: PMC4529364

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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