Article
Copy number alterations and allelic ratio in relation to recurrence of rectal cancer.
BMC genomics - 6 Jun 2015
Goossens-Beumer Inès J, Oosting Jan, Corver Wim E, Janssen Marjolein J F W, Janssen Bart, van Workum Wilbert, Zeestraten Eliane C M, van de Velde Cornelis J H, Morreau Hans, Kuppen Peter J K, van Wezel Tom
Abstract excerpt
BACKGROUND: In rectal cancer, total mesorectal excision surgery combined with preoperative (chemo)radiotherapy reduces local recurrence rates but does not improve overall patient survival, a result that may be due to the harmful side effects and/or co-morbidity of preoperative treatment. New biom...
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