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Article

Copy number alterations and allelic ratio in relation to recurrence of rectal cancer.

BMC genomics - 6 Jun 2015

Goossens-Beumer Inès J, Oosting Jan, Corver Wim E, Janssen Marjolein J F W, Janssen Bart, van Workum Wilbert, Zeestraten Eliane C M, van de Velde Cornelis J H, Morreau Hans, Kuppen Peter J K, van Wezel Tom

Abstract excerpt

BACKGROUND: In rectal cancer, total mesorectal excision surgery combined with preoperative (chemo)radiotherapy reduces local recurrence rates but does not improve overall patient survival, a result that may be due to the harmful side effects and/or co-morbidity of preoperative treatment. New biomarkers are needed to facilitate identification of rectal cancer patients at high risk for local recurrent disease. This...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26048403
DOI: 10.1186/s12864-015-1550-0
PMCID: PMC4458034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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