Article
Association Between CD147 Expression, RAS Mutational Status, and Local Recurrence in Resected Locally Advanced Rectal Cancer.
Cancer medicine - 1 Aug 2025
Isnard Anaëlle, Cramier Laure-Amandine, Vergara Rémi, Boubaddi Mehdi, Fouche Donatien, Fernandez Benjamin, Senant Nathalie, Denost Quentin, Rullier Éric, Dubus Pierre, Dabernat Sandrine, Dupin Charles, Vendrely Véronique, Rullier Anne, Amintas Samuel
Abstract excerpt
AIM: About 5% to 10% of rectal cancer (RC) patients experience local disease recurrence after chemoradiotherapy (CRT) and surgery. Identifying patients at high risk of local recurrence (LR) could lead to the personalized management of the patients. Multiple clinicopathological parameters are associated with LR. However, the potential of tumors for local regrowth may partially lie in the expression of pro-tumoral...
Read the complete abstract on PubMedTopics
- Humans
- Male
- Female
- Rectal Neoplasms
- Basigin
