Article
High-resolution analysis of DNA copy number alterations in rectal cancer: correlation with metastasis, survival, and mRNA expression.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] - 1 Oct 2014
Doyen Jérôme, Letouzé Eric, Marisa Laetitia, de Reyniès Aurélien, Milano Gérard, Etienne-Grimaldi Marie-Christine, Olschwang Sylviane, Gaedcke Jochen, Ghadimi Michael, Gérard Jean-Pierre
Abstract excerpt
BACKGROUND AND PURPOSE: This study aimed to determine the candidate genes and chromosomal imbalances capable of predicting occurrences of metastasis in patients with rectal cancer. PATIENTS AND METHODS: Fresh frozen tumor tissues from 80 patients with rectal cancer were prospectively collected and analyzed using Affymetrix HG-U133 Plus 2.0 gene expression arrays and high-resolution Illumina single-nucleotide...
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