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Article

Combined genetic effects of EGLN1 and VWF modulate thrombotic outcome in hypoxia revealed by Ayurgenomics approach.

Journal of translational medicine - 6 Jun 2015

Aggarwal Shilpi, Gheware Atish, Agrawal Anurag, Ghosh Saurabh, Prasher Bhavana, Mukerji Mitali

Abstract excerpt

BACKGROUND: Extreme constitution "Prakriti" types of Ayurveda exhibit systemic physiological attributes. Our earlier genetic study has revealed differences in EGLN1, key modulator of hypoxia axis between Prakriti types. This was associated with differences in high altitude adaptation and susceptibility to high altitude pulmonary edema (HAPE). In this study we investigate other molecular differences that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26047609
DOI: 10.1186/s12967-015-0542-9
PMCID: PMC4457985

Genes

EGLN1
VWF
LEPR
OLR1
SPTA1
UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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