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Genome-Wide Expression Analysis Suggests Hypoxia-Triggered Hyper-Coagulation Leading to Venous Thrombosis at High Altitude.

Thrombosis and haemostasis - 1 Jul 2018

Jha Prabhash Kumar, Sahu Anita, Prabhakar Amit, Tyagi Tarun, Chatterjee Tathagata, Arvind Prathima, Nair Jiny, Gupta Neha, Kumari Babita, Nair Velu, Bajaj Nitin, Shanker Jayashree, Sharma Manish, Kumar Bhuvnesh, Ashraf Mohammad Zahid

Abstract excerpt

Venous thromboembolism (VTE), a multi-factorial disease, is the third most common cardiovascular disease. Established genetic and acquired risk factors are responsible for the onset of VTE. High altitude (HA) also poses as an additional risk factor, predisposing individuals to VTE; however, its molecular mechanism remains elusive. This study aimed to identify genes/pathways associated with the pathophysiology of...

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PMID: 29864786
DOI: 10.1055/s-0038-1657770

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TEK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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