Modifying Role of GSTP1 Polymorphism on the Association between Tea Fluoride Exposure and the Brick-Tea Type Fluorosis.

doi:10.1371/journal.pone.0128280

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Article

Modifying Role of GSTP1 Polymorphism on the Association between Tea Fluoride Exposure and the Brick-Tea Type Fluorosis.

PloS one - 1 Jan 2015

Wu Junhua, Wang Wei, Liu Yang, Sun Jing, Ye Yan, Li Bingyun, Liu Xiaona, Liu Hongxu, Sun Zhenqi, Li Mang, Cui Jing, Sun Dianjun, Yang Yanmei, Gao Yanhui

Abstract excerpt

BACKGROUND: Brick tea type fluorosis is a public health concern in the north-west area of China. The association between SNPs of genes influencing bone mass and fluorosis has attracted attention, but the association of SNPs with the risk of brick-tea type of fluorosis has not been reported. OBJECTIVE: To investigate the modifying roles of GSTP1 rs1695 polymorphisms on this association. METHODS: A cross-sectional...

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PMID: 26046522
DOI: 10.1371/journal.pone.0128280
PMCID: PMC4457801

Genes

GSTP1

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