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Article

Progress of Signaling Pathways, Stress Pathways and Epigenetics in the Pathogenesis of Skeletal Fluorosis

3 Nov 2021

Abstract excerpt

Fluorine is widely dispersed in nature and has multiple physiological functions. Although it is usually regarded as an essential trace element for humans, this view is not held universally. Moreover, chronic fluorosis, mainly characterized by skeletal fluorosis, can be induced by long-term excessive fluoride consumption. High concentrations of fluoride in the environment and drinking water are major causes, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34769367
DOI: 10.3390/ijms222111932

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