Article
Matrix Metallopeptidase-2 Gene rs2287074 Polymorphism is Associated with Brick Tea Skeletal Fluorosis in Tibetans and Kazaks, China.
Scientific reports - 12 Jan 2017
Pei Junrui, Li Bingyun, Liu Yang, Liu Xiaona, Li Mang, Chu Yanru, Yang Qing, Jiang Wei, Chen Fuxun, Darko Gottfried M, Yang Yanmei, Gao Yanhui
Abstract excerpt
Brick tea skeletal fluorosis is still a public health issue in the north-western area of China. However its pathogenesis remains unknown. Our previous study reveals that the severity of skeletal fluorosis in Tibetans is more serious than that in Kazaks, although they have similar fluoride exposure, suggesting the onset of brick tea type skeletal fluorosis might be genetically influenced. Here we show that MMP-2...
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