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Article

Polymorphisms in ERCC1 and XPF gene and response to chemotherapy and overall survival of non-small cell lung cancer.

International journal of clinical and experimental pathology - 1 Jan 2015

Shi Zong-Hua, Shi Guang-Yong, Liu Lin-Gang

Abstract excerpt

We conducted a perspective study to assess the association between ERCC1 and XPF polymorphisms and response to chemotherapy and clinical outcome of NSCLC receiving chemotherapy. Between May 2009 and May 2011, a prospective study was conducted on 240 NSCLC cases. Genotypes of ERCC1 (rs11615, rs3212986 and rs2298881) and XPF (rs2276465 and rs6498486) were performed by Polymerase Chain Reaction Restriction Fragment...

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Share to Antineoplastic Combined Chemotherapy Protocols
Share to Carcinoma, Non-Small-Cell Lung
Share to Cisplatin
Share to Drug Resistance, Neoplasm
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Share to Kaplan-Meier Estimate
Share to Polymorphism, Restriction Fragment Length
Share to Proportional Hazards Models

Source

Open in PubMed Open full text

Identifiers

PMID: 26045829
PMCID: PMC4440138

Genes

ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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