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Article

Investigation on the DNA repaired gene polymorphisms and response to chemotherapy and overall survival of osteosarcoma.

International journal of clinical and experimental pathology - 1 Jan 2015

Ji Wei-Ping, He Neng-Bin

Abstract excerpt

The aim of the present study was to evaluate the influence of polymorphisms in NER and HRR pathways on the response to cisplatin-based treatment and clinical outcome in osteosarcoma patients. 214 osteosarcoma patients treated with cisplatin-based chemotherapy were collected between January 2008 and January 2011. Genotypes of ERCC1 rs11615, ERCC2 rs1799793 and rs13181, NBN rs709816, RAD51 rs1801320, and XRCC3...

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Topics

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Share to Bone Neoplasms
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Source

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Identifiers

PMID: 25755792
PMCID: PMC4348835

Genes

ERCC1
ERCC2
NBN
RAD51
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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