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Article

Association of ERCC1 Gene Polymorphisms (rs3212986 and rs11615) With the Risk of Lung Cancer in a Population From Southeast Iran.

Journal of research in health sciences - 30 Sept 2024

Khalouei Ali, Masoumi-Ardakani Yaser, Jafarzaheh Abdollah, Kalantari Khandani Behjat, Sedghy Farnaz, Khosravi Mashizi Arezu, Yaghoobi Mohammad Mehdi, Zangouey Mohammadreza, Shahouzehi Beydolah

Abstract excerpt

BACKGROUND: Polymorphisms within the excision repair cross-complementation group 1 (ERCC1), an essential component of DNA repair mechanisms, have been associated with various malignancies. This study aimed to evaluate the association of the single-nucleotide polymorphisms (SNPs) rs3212986 and rs11615 within the ERCC1 gene in non-small cell lung cancer (NSCLC) patients. Study Design: A case-control study. METHODS:...

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Identifiers

PMID: 39431656
DOI: 10.34172/jrhs.2024.166
PMCID: PMC11492521

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