Article
[Restoring phenotype of dedifferentiated normal nucleus pulposus cells by resveratrol].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery - 1 May 2013
Shen Jieliang, Hu Zhenming, Zhong Xiaoming, Wang Dawu, Xu Linfei
Abstract excerpt
OBJECTIVE: To investigate the effects of in-vitro monolayer culture and three-dimensional (3-D) alginate microsphere culture on the differentiation of normal human nucleus pulposus cells (NPCs), and to discuss the regulatory mechanism of restoring the phenotype of dedifferentiated NPCs by culturing resveratrol (RES) in 3-D alginate microsphere. METHODS: Normal human nucleus pulposus tissues were harvested for...
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