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Genetic variation in TLR pathway and the risk of pulmonary tuberculosis in a Moldavian population

5 Dec 2018

Abstract excerpt

Toll-like receptors (TLRs) play a critical role in initiating an immune response to infections. In this study, we examined whether single nucleotide polymorphisms (SNPs) in TLR pathway genes are associated with pulmonary tuberculosis (PTB) in a Moldavian population. Thirty-four SNPs in genes associated with the TLR pathway and two SNPs in ASAP1 gene identified by GWAS were selected for genotyping in 272 patients...

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PMID: 30529560
DOI: 10.1016/j.meegid.2018.12.005

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