Article
Resveratrol Decreases TXNIP mRNA and Protein Nuclear Expressions With an Arterial Function Improvement in Old Mice.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jun 2016
Bedarida Tatiana, Baron Stephanie, Vibert Françoise, Ayer Audrey, Henrion Daniel, Thioulouse Elizabeth, Marchiol Carmen, Beaudeux Jean-Louis, Cottart Charles-Henry, Nivet-Antoine Valerie
Abstract excerpt
Aging leads to a high prevalence of glucose intolerance and cardiovascular diseases, with oxidative stress playing a potential role. Resveratrol has shown promising effects on glucose tolerance and tends to improve endothelial function in elderly patients. Thioredoxin-interacting protein (TXNIP) was recently proposed as a potential link connecting glucose metabolism to oxidative stress. Here, we investigated the...
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