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Article

Impact of alcohol dehydrogenase gene 4 polymorphisms on esophageal squamous cell carcinoma risk in a Chinese population.

PloS one - 1 Jan 2015

Xu Xiaoling, Wang Jiwen, Zhu Shuang-Mei, Yang Ming, Fang Yun, Zhao An, Song Qian, Mao Weimin

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is very common in China and is also one of the most common cancers worldwide. The purpose of this study was to examine the associations between genetic variants of various cancer-related genes and the risk of ESCC. METHODS: In this study, we first examined the association between 18 potentially disruptive genetic variants of 17 genes, including alcohol...

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Source

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Identifiers

PMID: 26039424
DOI: 10.1371/journal.pone.0127304
PMCID: PMC4454665

Genes

ADH4
CHEK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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