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Article

Single nucleotide polymorphisms of ADH1B, ADH1C and ALDH2 genes and esophageal cancer: a population-based case-control study in China.

International journal of cancer - 15 Apr 2013

Wu Ming, Chang Shen-Chih, Kampman Ellen, Yang Jie, Wang Xu-Shan, Gu Xiao-Ping, Han Ren-Qiang, Liu Ai-Min, Wallar Gina, Zhou Jin-Yi, Kok Frans J, Zhao Jin-Kou, Zhang Zuo-Feng

Abstract excerpt

Alcohol drinking is a major risk factor for esophageal cancer (EC) and the metabolism of ethanol has been suggested to play an important role in esophageal carcinogenesis. Epidemiologic studies, including genomewide association studies (GWAS), have identified single nucleotide polymorphisms (SNPs) in alcohol dehydrogenases (ADHs) and aldehyde dehydrogenases (ALDHs) to be associated with EC. Using a...

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Source

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Identifiers

PMID: 22930414
DOI: 10.1002/ijc.27803
PMCID: PMC4122263

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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