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Article

IL-10 genetic polymorphisms were associated with valvular calcification in Han, Uygur and Kazak populations in Xinjiang, China.

PloS one - 1 Jan 2015

An Yong, Wang Yong-Tao, Ma Yi-Tong, Wulasihan Muhuyati, Huang Ying, Adi Dilare, Yang Yi-Ning, Ma Xiang, Li Xiao-Mei, Xie Xiang, Huang Ding, Liu Fen, Chen Bang-Dang

Abstract excerpt

OBJECTIVE: Valvular calcification occurs via ongoing endothelial injury associated with inflammation. IL-10 is an anti-inflammatory cytokine and 75% of the variation in IL-10 production is genetically determined. However, the relationship between genetic polymorphisms of IL-10 and valvular calcification has not been studied. The objective of this study was to investigate the association between valvular...

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Identifiers

PMID: 26039365
DOI: 10.1371/journal.pone.0128965
PMCID: PMC4454577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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