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Article

Blood and tissue neuroendocrine tumor gene cluster analysis correlate, define hallmarks and predict disease status

2 Jun 2015

Abstract excerpt

A multianalyte algorithmic assay (MAAA) identifies circulating neuroendocrine tumor (NET) transcripts (n=51) with a sensitivity/specificity of 98%/97%. We evaluated whether blood measurements correlated with tumor tissue transcript analysis. The latter were segregated into gene clusters (GC) that defined clinical 'hallmarks' of neoplasia. A MAAA/cluster integrated algorithm (CIA) was developed as a predictive...

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PMID: 26037279
DOI: 10.1530/erc-15-0092

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