Article
Maltose-Dependent Transcriptional Regulation of the mal Regulon by MalR in Streptococcus pneumoniae.
PloS one - 1 Jan 2015
Afzal Muhammad, Shafeeq Sulman, Manzoor Irfan, Kuipers Oscar P
Abstract excerpt
The maltose regulon (mal regulon) has previously been shown to consist of the mal gene cluster (malMP, malXCD and malAR operons) in Streptococcus pneumoniae. In this study, we have further elucidated the complete mal regulon in S. pneumoniae D39 using microarray analyses and β-galactosidase assays. In addition to the mal gene cluster, the complete mal regulon of S. pneumoniae D39 consists of a pullulanase (PulA),...
Topics
- Bacterial Proteins
- Base Sequence
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Glucose
- Maltose
- Molecular Sequence Data
- Mutation
- Oligonucleotide Array Sequence Analysis
- Operator Regions, Genetic
- Operon
- Regulon
- Repressor Proteins
- Streptococcus pneumoniae
- Transcription, Genetic
- Transcriptome