Article
Genome-wide transcriptional profiling in human squamous cell carcinoma of the skin identifies unique tumor-associated signatures.
The Journal of dermatology - 1 May 2006
Kathpalia Vinnie P, Mussak Erich N, Chow Selwyn S, Lam Phillip H, Skelley Nathan, Time Michael, Markelewicz Robert J, Kanduc Darja, Lomas Lucy, Xiang Zhaoying, Sinha Animesh A
Abstract excerpt
The elucidation of specific genetic changes associated with human cancer pathogenesis has focused efforts to relate such changes to the neoplastic phenotype. To further our understanding of the genetic basis of human squamous cell carcinoma (SCC) of the skin, this study used a genome-wide (12 627 sequences) approach to determine transcriptional signatures in lesional and nonlesional sites from five SCC patients....
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