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Article

Squamous Cell Cancers: A Unified Perspective on Biology and Genetics.

Cancer cell - 9 May 2016

Dotto G Paolo, Rustgi Anil K

Abstract excerpt

Squamous cell carcinomas (SCCs) represent the most frequent human solid tumors and are a major cause of cancer mortality. These highly heterogeneous tumors arise from closely interconnected epithelial cell populations with intrinsic self-renewal potential inversely related to the stratified differentiation program. SCCs can also originate from simple or pseudo-stratified epithelia through activation of quiescent...

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Identifiers

PMID: 27165741
DOI: 10.1016/j.ccell.2016.04.004
PMCID: PMC4870309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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