Article
Squamous cell carcinoma of unknown primary (SCCUP): a genomic landscape study.
ESMO open - 1 Jun 2025
Robinson H R, Lakritz S, Pavlick D C, Davis S L, Lieu C H, Eule C J, Graham L S, Spiess P E, Li R, Kamat A M, Grivas P, Jacob J M, Bratslavsky G, Basnet A, Wong K A, Lin D I, Necchi A, Ross J S, Lam E T
Abstract excerpt
BACKGROUND: Squamous cell carcinoma (SCC) of unknown primary (SCCUP) refers to any SCC for which the primary tumor origin cannot be identified despite guideline-directed evaluation. Although strategies employing comprehensive genomic profiling (CGP) to identify targets for non-SCC carcinomas of unknown primary (CUPs) have shown benefit, the genomic landscape in SCCUP remains poorly defined. Here we describe...
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- Humans
- Neoplasms, Unknown Primary
- Carcinoma, Squamous Cell
- Female
- Male
- Middle Aged