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Article

Thyroid Hormone Receptors Predict Prognosis in BRCA1 Associated Breast Cancer in Opposing Ways.

PloS one - 1 Jan 2015

Heublein Sabine, Mayr Doris, Meindl Alfons, Angele Martin, Gallwas Julia, Jeschke Udo, Ditsch Nina

Abstract excerpt

Since BRCA1 associated breast cancers are frequently classified as hormone receptor negative or even triple negative, the application of endocrine therapies is rather limited in these patients. Like hormone receptors that bind to estrogen or progesterone, thyroid hormone receptors (TRs) are members of the nuclear hormone receptor superfamily. TRs might be interesting biomarkers - especially in the absence of...

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Share to BRCA1 Protein
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Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Receptors, Thyroid Hormone

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Source

Open in PubMed Open full text

Identifiers

PMID: 26029931
DOI: 10.1371/journal.pone.0127072
PMCID: PMC4451081

Genes

BRCA1
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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