Article
Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas.
Diagnostic pathology - 15 May 2013
Klingen Tor A, Chen Ying, Suhrke Pål, Stefansson Ingunn M, Gundersen Marian D, Akslen Lars A
Abstract excerpt
BACKGROUND: The differential diagnosis between primary and secondary breast cancers might be difficult, especially in poorly differentiated tumors. Thyroid Transcription Factor-1 (TTF-1) has been regarded as a reliable marker for lung or thyroid origin, with only occasional positive staining in other tumors. However, positive cases have recently been reported among primary breast carcinomas. METHODS AND RESULTS:...
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