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Article

Higher DEFB4 genomic copy number in SLE and ANCA-associated small vasculitis.

Rheumatology (Oxford, England) - 1 Jun 2012

Zhou Xu-Jie, Cheng Fa-Juan, Lv Ji-Cheng, Luo Huan, Yu Feng, Chen Min, Zhao Ming-Hui, Zhang Hong

Abstract excerpt

OBJECTIVE: Evidence shows that defensins are involved in the pathogenesis of SLE and ANCA-associated small vasculitis (AASV). The copy number variation of DEFB4 has been proposed to be susceptible to inflammatory disorders. This study aims to investigate whether the DEFB4 genomic copy number variations associate with the susceptibility to these two autoimmune diseases. METHODS: A total of 1178 Chinese people were...

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Share to Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22302058
DOI: 10.1093/rheumatology/ker419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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