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Article

Copy number variation of β-defensin genes in Behçet's disease.

Clinical and experimental rheumatology - 1 Jan 2000

Park Jin Joo, Oh Boram R, Kim Joung Yeon, Park Ji Ah, Kim Chul, Lee Yun Jong, Song Yeong Wook, Armour John A L, Lee Eun Bong

Abstract excerpt

OBJECTIVES: Behçet's disease (BD) may be triggered by infectious agents in genetically susceptible persons. Human β-defensin 2 is an inducible antimicrobial peptide, the level of which can be influenced by copy number (CN) of the DEFB4. We investigated the relationship between copy number variation (CNV) of DEFB4 and BD. METHODS: One hundred and ninety-seven patients with BD and 197 healthy controls were...

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PMID: 21385545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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