Article
Analysis of HLA-G long-read genomic sequences in mother-offspring pairs with preeclampsia.
Scientific reports - 18 Nov 2020
Nishizawa Ayako, Kumada Kazuki, Tateno Keiko, Wagata Maiko, Saito Sakae, Katsuoka Fumiki, Mizuno Satoshi, Ogishima Soichi, Yamamoto Masayuki, Yasuda Jun, Sugawara Junichi
Abstract excerpt
Preeclampsia is a pregnancy-induced disorder that is characterized by hypertension and is a leading cause of perinatal and maternal-fetal morbidity and mortality. HLA-G is thought to play important roles in maternal-fetal immune tolerance, and the associations between HLA-G gene polymorphisms and the onset of pregnancy-related diseases have been explored extensively. Because contiguous genomic sequencing is...
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